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Common Vaccines for Overseas Travelers


Vaccine ( Click on link for more info) Standard regimen Booster Age Adverse effects Notes
Hepatitis A  
Havrix 1.0 mL IM 1.0 mL IM 6 to 12 months after first dose >= 19 years† Injection site soreness, headaches Safety in pregnancy not determined

although still uncertain completed 2 Dose series of any hepatitis A vaccine may give life long immunity

Vaqta 1.0 mL IM 1.0 mL IM 6 to 12 months after first dose >= 19 years† Injection site soreness, headaches
Hepatitis B  
HB Vax II1.0 mL IM at 0, 1, and 6 months , or 2 doses at 0 and 6 months for 11-15 yr olds (Paed dose)A further booster is not routine >= 20 years† Injection site soreness, headaches Safety in pregnancy not determined
Contraindicated in yeast hypersensitivity
Engerix-B 1.0 mL IM at 0, 1, and 6 months
(Accelerated schedule: 1.0 mL IM at 0, 1, 2, and 12 months)
1.0 mL IM 12 months after first dose >= 20 years† Injection site soreness, headaches
Combined hepatitis A and hepatitis B  
Twinrix 1.0 mL IM at 0, 1, and 6 months Not routine >= 18 years Injection site soreness, headaches, nausea Safety in pregnancy not determined
Contraindicated in yeast hypersensitivity . May give lifelong immunity.
Combined hepatitis A and typhoid
VivaximSingle dose 1 ml combined vaccine Not Routine>=16 yrs Injection site soreness Lifelong immunity to hepatitis B can be achieved by giving a second dose six to 12 months later. Typhoid immunity probably three years

Pregnancy safety not established

Japanese encephalitis  
Japanese Encephalitis Vaccine1.0 mL SI on days 0, 7, 30 1.0 mL SI every 2 to 3 years >= 3 years Fever, headache, nausea, vomiting (urticaria and angioedema are rare) Safety in pregnancy not determined
Administer last dose 10 days before trip departure
Meningococcal type C 
 Mencevax0.5 mL SI 0.5 mL SI every 3 to 5 years >= 2 years Injection site soreness Safe in pregnancy
Typhoid fever  
Oral Typhoid Vax Threecapsules: 1 capsule given every other day - start day 28 before travel; i.e. Day 28, 26 & 24Three capsule regimen every 5 years >= 6 years Nausea, vomiting, cramping, fever Oral Thypoid vaccine capsules must be kept refrigerated; each capsule should be taken whole (do not chew) with cool liquid one hour before a meal
Oral Typoid vaccine contraindicated in pregnancy and immunocompromised patients
Start mefloquine (Lariam) or chloroquine  at least 3 days after completion of oral Typhoid vaccine
Safety of Typhim VI vaccine in pregnancy not determined
Typhim VI 0.5 mL IM 0.5 mL IM every 2 years >= 2 years Nausea, vomiting, cramping
Yellow fever  
Stamaril0.5 mL SI 0.5 mL SI every 10 years >= 9 months Headaches, myalgias, fever, encephalitis (rarely in the elderly) Consider carefully in elderly patients
Contraindicated in pregnancy, patients with egg allergy, and immunocompromised patients
Avoid concurrent administration with other live virus vaccines (MMR, oral polio, varicella, oral Typhoid)

IM = intramuscularly; SI = subcutaneously; MMR = measles-mumps-rubella vaccine.

†-Pediatric concentration of vaccine available and/or requires different dosage regimen.